Clemens Kocken is Chairman of the Department of Parasitology at the Biomedical Primate Research Centre (BPRC), Rijswijk. After graduation from Groningen Universtity, The Netherlands in 1984 Biochemistry/Molecular Biology), Clemens Kocken obtained a PhD at the same university in 1989 with a thesis entitled “Recombinant Fusion Proteins of Herpes Simplex Virus Type 1 Glycoprotein D- expression in Escherichia coli, purification and immunological properties”.
He then held a postdoctoral position for five years at Nijmegen University, where he worked on malaria transmission-blocking vaccine development. In 1994 he joined BPRC to work in Alan Thomas’ Parasitology Department. Here he worked on the development of AMA1 as a malaria vaccine candidate, on developing non-human primate malaria drug models, and on transfection systems for non-human primate malarias.
The research of the Department of Parasitology is focused on developing vaccines and drugs against malaria and TB, using non-human primate models. Current topics include vaccine efficacy testing and immune correlates of TB, AMA1 as a malaria blood stage vaccine candidate in clinical development and development of new drugs active against malaria hypnozoites.