Accelerated phase Ia/b evaluation of the malaria vaccine candidate PfAMA1 DiCo demonstrates broadening of humoral immune responses

Remarque EJ, Faber BW, Rodriguez Garcia R, Oostermeijer H, Sirima SB, Ouedraogo IN, Kara L, Launay O, Houard S, Leroy O, and Kocken CHM

npj Vaccines 2021 6: 55


PRIMVAC vaccine adjuvanted with Alhydrogel or GLA-SE to prevent placental malaria: a first-in-human, randomised, double-blind, placebo-controlled study.

Sirima SB, Richert L, Chêne A, Konate AT, Campion C, Dechavanne S, Semblat JP, Benhamouda N, Bahuaud M, Loulergue P, Ouédraogo A, Nébié I, Kabore M, Kargougou D, Barry A, Ouattara SM, Boilet V, Allais F, Roguet G, Havelange N, Lopez-Perez E, Kuppers A, Konaté E, Roussillon C, Kanté M, Belarbi L, Diarra A, Henry N, Soulama I, Ouédraogo A, Esperou H, Leroy O, Batteux F, Tartour E, Viebig NK, Thiebaut R, Launay O, Gamain B.

Lancet Infect Dis. 2020 May;20(5):585-597.


Epitope Mapping and Fine Specificity of Human T and B Cell Responses for Novel Candidate Blood-Stage Malaria Vaccine P27A.

Geiger KM, Guignard D, Yang C, Bikorimana JP, Correia BE, Houard S, Mkindi C, Daubenberger CA, Spertini F, Corradin G, Audran R.

Front Immunol. 2020 Mar 10;11:412.


Editorial: A Global Perspective on Vaccines: Priorities, Challenges and Online Information.

Tagliabue A, Leite LCC, Leroy OY, Rappuoli R.

Front Immunol. 2019 Nov 12;10:2556.


First-in- human, Randomized, Double-blind Clinical Trial of Differentially Adjuvanted PAMVAC, A Vaccine Candidate to Prevent Pregnancy-associated Malaria.

Mordmüller B, Sulyok M, Egger-Adam D, Resende M, de Jongh WA, Jensen MH, Smedegaard HH, Ditlev SB, Soegaard M, Poulsen L, Dyring C, Calle CL, Knoblich A, Ibáñez J, Esen M, Deloron P, Ndam N, Issifou S, Houard S, Howard RF, Reed SG, Leroy O, Luty AJF, Theander TG, Kremsner PG, Salanti A, Nielsen MA.

Clin Infect Dis. 2019 Oct 15;69(9):1509-1516.


The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCRβ clonotypes.

Hill DL, Pierson W, Bolland DJ, Mkindi C, Carr EJ, Wang J, Houard S, Wingett SW, Audran R, Wallin EF, Jongo SA, Kamaka K, Zand M, Spertini F, Daubenberger C, Corcoran AE, Linterman MA.

J Exp Med. 2019 Aug 5;216(8):1857-1873.


Pipeline analysis of a vaccine candidate portfolio for diseases of poverty using the Portfolio-To-Impact modelling tool.

Gunn A, Bandara S, Yamey G, D Alessio F, Depraetere H, Houard S, Viebig NK, Jungbluth S.

F1000Res. 2019 Jul 11;8:1066


Preclinical immunogenicity and safety of the cGMP-grade placental malaria vaccine PRIMVAC.

Chêne A, Gangnard S, Guadall A, Ginisty H, Leroy O, Havelange N, Viebig NK, Gamain B.

EBioMedicine. 2019 Apr;42:145-156.


Eligibility for Local Therapies in Adolescents and Adults with Cutaneous Leishmaniasis from Southwestern Colombia: A Cross-Sectional Study.

Uribe-Restrepo AF, Prieto MD, Cossio A, Desai MM, Castro MDM.

Study. Am J Trop Med Hyg. 2019 Feb;100(2):306-310.


The Candidate Blood- stage Malaria Vaccine P27A Induces a Robust Humoral Response in a Fast Track to the Field Phase 1 Trial in Exposed and Nonexposed Volunteers.

Steiner-Monard V, Kamaka K, Karoui O, Roethlisberger S, Audran R, Daubenberger C, Fayet-Mello A, Erdmann-Voisin A, Felger I, Geiger K, Govender L, Houard S, Huber E, Mayor C, Mkindi C, Portevin D, Rusch S, Schmidlin S, Tiendrebeogo RW, Theisen M, Thierry AC, Vallotton L, Corradin G, Leroy O, Abdulla S, Shekalaghe S, Genton B, Spertini F, Jongo SA.

Clin Infect Dis. 2019 Jan 18;68(3):466-474.


Interventions to treat cutaneous leishmaniasis in children: A systematic review.

Uribe-Restrepo A, Cossio A, Desai MM, Dávalos D, Castro MDM.

PLoS Negl Trop Dis. 2018 Dec 14;12(12):e0006986.


First field efficacy trial of the ChAd63 MVA ME- TRAP vectored malaria vaccine candidate in 5-17 months old infants and children.

Tiono AB, Nébié I, Anagnostou N, Coulibaly AS, Bowyer G, Lam E, Bougouma EC, Ouedraogo A, Yaro JBB, Barry A, Roberts R, Rampling T, Bliss C, Hodgson S, Lawrie A, Ouedraogo A, Imoukhuede EB, Ewer KJ, Viebig NK, Diarra A, Leroy O, Bejon P, Hill AVS, Sirima SB.

PLoS One. 2018 Dec 12;13(12):e0208328.


Workshop report: Experimental animal models for universal influenza vaccines.

D'Alessio F, Koopman G, Houard S, Remarque EJ, Stockhofe N, Engelhardt OG.

Vaccine. 2018 Nov 12;36(46):6895-6901.


An international qualitative study exploring patients' experiences of cutaneous leishmaniasis: study set-up and protocol.

Erber AC, Arana B, Bennis I, Ben Salah A, Boukthir A, Castro Noriega MDM, Cissé M, Cota GF, Handjani F, Kebede MG, Lang T, López Carvajal L, Marsh K, Martinez Medina D, Plugge E, Olliaro P.

BMJ Open. 2018 Jun 15;8(6):e021372


Recommendations of the VAC2VAC workshop on the design of multi-centre validation studies.

Halder M, Depraetere H, Delannois F, Akkermans A, Behr-Gross ME, Bruysters M, Dierick JF, Jungbäck C, Kross I, Metz B, Pennings J, Rigsby P, Riou P, Balks E, Dobly A, Leroy O, Stirling C.

Biologicals. 2018 Mar;52:78-82.