2012

Ibison F, Olotu A, Muema DM, Mwacharo J, Ohuma E, Kimani D, Marsh K, Bejon P and Ndungu FM. Lack of Avidity Maturation of Merozoite Antigen-Specific Antibodies with Increasing Exposure to Plasmodium falciparum Amongst Children and Adults Exposed to Endemic Malaria in Kenya. PLoS One, 2012;7(12):e52939. doi: 10.1371/journal.pone.0052939. Epub 2012 Dec 26 (MVVC)

Anthony Ajua, Thomas Engleitner, Meral Esen, Michael Theisen, Saadou Issifou, Benjamin Mordmüller.  A flow cytometry-based workflow for detection and quantification of anti-plasmodial antibodies in vaccinated and naturally exposed individuals. Malaria Journal201211:367 DOI: 10.1186/1475-2875-11-367 (EMVDA)

Maertzdorf J, Weiner J 3rd, Kaufmann SH.  Enabling biomarkers for tuberculosis control.Int J Tuberc Lung Dis. 2012 Sep;16(9):1140-8. doi: 10.5588/ijtld.12.0246 (TRANSVAC)

Rueckert C, Guzmán CA.  Vaccines: from empirical development to rational design. PLoS Pathog. 2012;8(11):e1003001. doi: 10.1371/journal.ppat.1003001. Epub 2012 Nov 8 (TRANSVAC)

Libanova R. Becker PD, Guzmán CA.  Cyclic di-nucleotides: new era for small molecules as adjuvants. Microb Biotechnol. 2012 Mar;5(2):168-76. doi: 10.1111/j.1751-7915.2011.00306.x. Epub 2011 Sep 29 (TRANSVAC)

Caroline Kulangara, Samuel Luedin, Olivier Dietz, Sebastian Rusch, Geraldine Frank, Dania Mueller, Mirjam Moser, Andrey V. Kajava, Giampietro Corradin, Hans-Peter Beck, Ingrid Felger. Cell Biological Characterization of the Malaria Vaccine Candidate Trophozoite Exported Protein 1. PLOS One, vol 7, issue 10, e46112 (P27A)

Remarque EJ, Roestenberg M, Younis S, Walraven V, van der Werff N, Faber BW, Leroy O, Sauerwein R, Kocken CH, Thomas AW.  Humoral immune responses to a single allele PfAMA1 vaccine in healthy malaria-naïve adults. PLoS One. June 2012 7(6):e38898 (AMA1)

The Malaria Vectored Vaccines Consortium (MVVC) article Vaccine Ventures is based on an interview with EVI's Clinical and Regulatory Affairs Director and MVVC Project Coordinator, Egeruan Babatunde Imoukhuede published in International Innovation, Healthcare, May 2012, issue 15. (MVVC)

Kaufmann SH.   Tuberculosis vaccine development: strength lies in tenacity. Trends Immunol. 2012 Jul;33(7):373-9. doi: 10.1016/j.it.2012.03.004. Epub 2012 May 3. (TRANSVAC)

Ndungu FM, Olotu A, Mwacharo J, Nyonda M, Apfeld J, Mramba LK, Fegan GW, Bejon P, Marsh K. Memory B cells are a more reliable archive for historical antimalarial responses than plasma antibodies in no-longer exposed children. Proc Natl Acad Sci USA. 2012 May 22;109(21):8247-52. doi: 10.1073/pnas.1200472109. Epub 2012 May7 (MVVC)

Ndibazza J, Mpairwe H, Webb EL, Mawa PA, Nampijja M, Muhangi L, Kihembo M, Lule SA, Rutebarika D, Apule B, Akello F, Akurut H, Oduru G, Naniima P, Kizito D, Kizza M, Kizindo R, Tweyongyere R, Alcock K, Muwanga M, Elliott AM. Impact of anthelminthic treatment in pregnancy and early childhood on response to immunisation and on the incidence of infectious diseases and eczema in early childhood: results of a randomised, double-blind, placebo-controlled trial. PLoS One 2012 7:e50325 (IDEA)

Emily L. Webb, Andrew Obuku Ekii and Pietro Pala Epidemiology and immunology of helminth-HIV interactions. Current Opinion in HIV and AIDS 2012 7:245-53 (IDEA)

Van der Vlugt LE, Labuda LA, Ozir-Fazalalikhan A, Lievers E, Gloudemans AK, Liu KY, Barr TA, Sparwasser T, Boon L, Ngoa UA, Feugap EN, Adegnika AA, Kremsner PG, Gray D, Yazdanbakhsh M, Smits HH. Schistosomes induce regulatory features in human and mouse CD1d(hi) B cells: inhibition of allergic inflammation by IL-10 and regulatory T cells, PLoS One 2012;7(2):e30883 (IDEA)

Ndungu FM, Mwacharo J, Kimani D, Kai O, Moris P, Jonger E, Vekemans J, Olotu A, Bejon P.  A Statistical Interaction Between Circumsporozoite Protein-Specific T cell and Antibody Responses and Risk of Clinical Malaria Episodes Following Vaccination with RTS,S/AS01E. PLoS One. 2012;7(12):e52870. doi: 10.1371/journal.pone.0052870. Epub 2012 Dec 27 (MVVC)

Elliott A, Yazdanbakhsh M. Troubles never come alone. Curr Opin HIV AIDS 2012, VMay;7(3):211-3 (IDEA)

Petruccioli E, Romagnoli A, Corazzari M, Coccia EM, Butera O, Delogu G, Piacentini M, Girardi E, Fimia GM, Goletti D. Specific T Cells Restore the Autophagic Flux Inhibited by Mycobacterium tuberculosis in Human Primary Macrophages. J Infect Dis  2012 May; 205(9):1425-35 (IDEA)

Brooker SJ, Pullan RL, Gitonga CW, Ashton RA, Kolaczinski JH, Kabatereine NB & Snow RW (2012) Plasmodium-helminth coinfection and its sources of heterogeneity across East Africa. Journal of Infectious Diseases 2012 205(5), 841-852 (IDEA)

R.E. Thom, M.J. Elmore, A. Williams, S.C. Andrews, F. Drobniewski, P.D. Marsh, and J.A. Tree.  The expression of ferritin, lactoferrin, transferrin receptor and solute carrier family 11A1 in the host response to BCG-vaccination and Mycobacterium tuberculosis challenge.Vaccine, vol. 30, issue 21, 2 May 2012, 3159 - 3168 (TRANSVAC)

J.A. Tree, S. Smith, N. Baker, S. Clark, F.E. Aldwell, M. Chambers, A. Williams, and P.D. Marsh.  Method for assessing IFN-c responses in guinea pigs during TB vaccine trials.Letters in Applied Microbiology, vol. 55, issue 4, 295 - 300 Oct. 2012 (TRANSVAC)

Grode L. Ganoza CA, Brohm C, Weiner J 3rd, Eisele B, Kaufmann SH. (2013).  Safety and immunogenicity of the recombinant BCG vaccine VPM1002 in a phase 1 open-label randomized clinical trial.  Vaccine 2012, 31(9): 1340-1348 (TRANSVAC)