2015

Kepha S, Nuwaha F, Nikolay B, Gichuki P, Mwandawiro CS, Mwinzi PN, Odiere MR, Edwards T, Allen E, Brooker SJ.  Effect of Repeated Anthelminthic Treatment on Malaria in School Children in Kenya: A Randomized, Open-Label, Equivalence Trial.  J Infect Dis. 2015 Jul 13. pii: jiv382. [Epub ahead of print] (IDEA)

Salim N, Knopp S, Lweno O, Abdul U, Mohamed A, Schindler T, Rothen J, Masimba J, Kwaba D, Mohammed AS, Althaus F, Abdulla S, Tanner M, Daubenberger C, Genton B.  Distribution and risk factors for Plasmodium and helminth co-infections: a cross-sectional survey among children in Bagamoyo district, coastal region of Tanzania.  PLoS Negl Trop Dis. 2015 Apr 2;9(4):e0003660. doi: 10.1371/journal.pntd.0003660 (IDEA)

Mawa PA, Nkurunungi G, Egesa M, Webb EL, Smith SG, Kizindo R, Akello M, Lule SA, Muwanga M, Dockrell HM, Cose S, Elliott AM.  The impact of maternal infection with Mycobacterium tuberculosis on the infant response to bacille Calmette-Guérin immunization.  Philos Trans R Soc Lond B Biol Sci. 2015 Jun 19;370(1671). pii: 20140137. doi: 10.1098/rstb.2014.0137 (IDEA)

Biraro IA, Egesa M, Toulza F, Levin J, Cose S, Joloba M, Smith S, Dockrell HM, Katamba A, Elliott AM.  Impact of co-infections and BCG immunisation on immune responses among household contacts of tuberculosis patients in a Ugandan cohort. PLoS One. 2014 Nov 5;9(11):e111517. doi: 10.1371/journal.pone.0111517. eCollection 2014 (IDEA)

van der Vlugt LE, Zinsou JF, Ozir-Fazalalikhan A, Kremsner PG, Yazdanbakhsh M, Adegnika AA, Smits HH  Interleukin 10 (IL-10)-producing CD1dhi regulatory B cells from Schistosoma haematobium-infected individuals induce IL-10-positive T cells and suppress effector T-cell cytokines. J Infect Dis. 2014 Oct 15;210(8):1207-16. doi: 10.1093/infdis/jiu257  (IDEA)

Stax MJ, Mouser EE, van Montfort T, Sanders RW, de Vries HJ, Dekker HL, Herrera C, Speijer D, Pollakis G, Paxton WA.  Colorectal mucus binds DC-SIGN and inhibits HIV-1 trans-infection of CD4+ T-lymphocytes. PLoS One. 2015 Mar 20;10(3):e0122020. doi: 10.1371/journal.pone.0122020. eCollection 2015 (IDEA)

Ateba-Ngoa U, Adegnika AA, Zinsou JF, Kassa Kassa RF, Smits H, Massinga-Loembe M, Mordmüller B, Kremsner PG, Yazdanbakhsh M.  Cytokine and chemokine profile of the innate and adaptive immune response of schistosoma haematobium and plasmodium falciparum single and co-infected, school-aged children from an endemic area of Lambaréné, Gabon. Malar J. 2015 Feb 25;14:94. doi: 10.1186/s12936-015-0608-4 (IDEA)

Ssetaala A, Nakiyingi-Miiro J, Asiki G, Kyakuwa N, Mpendo J, Van Dam GJ, Corstjens PL, Pala P, Nielsen L, Bont J, Pantaleo G, Kiwanuka N, Kaleebu P, Kamali A, Elliott AM. Schistosoma mansoni and HIV acquisition in fishing communities of Lake Victoria, Uganda: a nested case-control study. Trop Med Int Health. 2015 Sep;20(9):1190-1195. doi: 10.1111/tmi.12531. Epub 2015 May 27 (IDEA)

Hussaarts L, García-Tardón N, van Beek L, Heemskerk MM, Haeberlein S, van der Zon GC, Ozir-Fazalalikhan A, Berbée JF, Willems van Dijk K, van Harmelen V, Yazdanbakhsh M, Guigas B.  Chronic helminth infection and helminth-derived egg antigens promote adipose tissue M2 macrophages and improve insulin sensitivity in obese mice. FASEB J.2015 Jul;29(7):3027-39. doi: 10.1096/fj.14-266239. Epub 2015 Apr 7 (IDEA)

Kepha S, Nuwaha F, Nikolay B, Gichuki P, Edwards T, Allen E, Njenga SM, Mwandawiro CS, Brooker SJ.  Epidemiology of coinfection with soil transmitted helminths and Plasmodium falciparum among school children in Bumula District in western Kenya.Parasit Vectors. 2015 Jun 11;8:314. doi: 10.1186/s13071-015-0891-5 (IDEA)

Petruccioli E, Petrone L, Vanini V, Cuzzi G, Navarra A, Gualano G, Palmieri F, Girardi E, Goletti D.  Assessment of CD27 expression as a tool for active and latent tuberculosis diagnosis. J Infect. 2015 Nov;71(5):526-33. doi: 10.1016/j.jinf.2015.07.009. Epub 2015 Aug 5 (IDEA)

Petrone L, Vanini V, etruccioli E, Ettorre GM, Busi Rizzi E, Schininà V, Girardi E, Ludovisi A, Gómez-Morales MÁ, Pozio E, Teggi A, Goletti D.  IL-4 specific-response in whole blood associates with human Cystic Echinococcosis and cyst activity. J Infect. 2015 Mar;70(3):299-306. doi: 10.1016/j.jinf.2014.10.009. Epub 2014 Oct 22 (IDEA)

Boer MC, Prins C, van Meijgaarden KE, van Dissel JT, Ottenhoff TH, Joosten SA. Mycobacterium bovis BCG Vaccination Induces Divergent Proinflammatory or Regulatory T Cell Responses in Adults. Clin Vaccine Immunol. 2015 Jul;22(7):778-88. doi: 10.1128/CVI.00162-15. Epub 2015 May 6 (IDEA)

Boer MC, Joosten SA, Ottenhoff TH.  Regulatory T-Cells at the Interface between Human Host and Pathogens in Infectious Diseases and Vaccination. Front Immunol. 2015 May 11;6:217. doi: 10.3389/fimmu.2015.00217. eCollection 2015 (IDEA)

Anne C. Teirlinck, Meta Roestenberg, Else M. Bijker, Stephen L. Hoffman, Robert W. Sauerwein, Anja Scholzen.  Plasmodium falciparum Infection of Human Volunteers Activates Monocytes and CD16+ Dendritic Cells and Induces Upregulation of CD16 and CD1c Expression. Infect Immun, v.83(9); 2015 Sep, PMC4534665 (EMVDA)

Nicola K. Viebig, Flavia D’Alessio, Simon J. Draper, B. Kim Lee Sim, Benjamin Mordmüller, Paul W. Bowyer, Adrian J.F. Luty, Stefan Jungbluth, Chetan E. Chitnis,Adrian V.S. Hill, Peter Kremsner, Alister G. Craig, Clemens H.M. Kocken, Odile Leroy.  Malaria vaccine development in Europe - preparing for the future.  Vaccine, vol. 33, issue 46, 17 November 2015

Morten A. Nielsen  , Mafalda Resende, Willem A. de Jongh, Sisse B. Ditlev, Benjamin Mordmüller, Sophie Houard, Nicaise Tuikue Ndam, Mette Ø. Agerbæk, Mette Hamborg, Achille Massougbodji, Saddou Issifou, Anette Strøbæk, Lars Poulsen, Odile Leroy, Peter G. Kremsner, Jean-Philippe Chippaux5,, Adrian J. F. Luty, Philippe Deloron, Thor G. Theander, Charlotte Dyring, Ali Salanti.  The Influence of Sub-Unit Composition and Expression System on the Functional Antibody Response in the Development of a VAR2CSA Based Plasmodium falciparum Placental Malaria Vaccine.  PLoS ONE 10(9): e0135406. doi: 10.1371/journal.pone.0135406 (PAMCPH)

Geels M, Thøgersen RL, Guzman CA, Ho MM, Verreck F, Collin N, Robertson JS, McConkey SJ, Kaufmann SH, Leroy O.  TRANSVAC research infrastructure - Results and lessons learned from the European network of vaccine research and development. Vaccine. 2015 Oct 5;33(41):5481-7. doi: 10.1016/j.vaccine.2015.01.079. Epub 2015 Feb 8 (TRANSVAC)

Michalis Kotsyfakis, Petr Kopáček, Zdeněk Franta, Joao H. F. Pedra, José M. C. Ribeiro.  Deep Sequencing Analysis of the Ixodes ricinus Haemocytome.  PLOS Neglected Tropical Diseases DOI:10.1371/journal.pntd.00037 (TRANSVAC)

Caroline Ogwang, Domtila Kimani, Nick J. Edwards, Rachel Roberts, Jedidah Mwacharo, Georgina Bowyer, Carly Bliss, Susanne H. Hodgson, Patrica Njuguna, Nicola K. Viebig,  Alfredo Nicosia, Evelyn Gitau, Sandy Douglas, Joe Illingworth, Kevin Marsh, Alison Lawrie, Egeruan B. Imoukhuede, Katie Ewer, Britta C. Urban, Adrian V. S. Hill, Philip Bejon, the MVVC group Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against Plasmodium falciparum infection in Kenyan adult.  Sci Transl Med 6 May 2015: Vol. 7, issue 286, DOI: 10.1126/ scitranslmed.aaa2373 (MVVC)

Chetan E. Chitnis, Paushali Mukherjee, Shantanu Mehta, Syed Shams Yazdani, Shikha Dhawan, Ahmad Rushdi Shakri, Rukmini Bharadwaj, Puneet Kumar Gupta, Dhiraj Hans, Suman Mazumdar, Bijender Singh, Sanjeev Kumar, Gaurav Pandey, Varsha Parulekar, Nathalie Imbault, Preethi Shivyogi, Girish Godbole, Krishna Mohan, Odile Leroy, Kavita Singh, Virander S. Chauhan.  Phase I Clinical Trial of a Recombinant Blood Stage Vaccine Candidate for Plasmodium falciparum Malaria Based on MSP1 and EBA175.  PLOS one, 30 April 2015, DOI: 10.1371/journal.pone.0117820 (JAIVAC)

Kotsyfakis M, Schwarz A, Erhart J, Ribeiro JM.  Tissue- and time-dependent transcription in Ixodes ricinus salivary glands and midguts when blood feeding on the vertebrate host. Sci Rep. 2015 Mar 13;5:9103. doi: 10.1038/srep09103 (TRANSVAC)

Andrea Rachow A, Heinrich N, Geldmacher C.  Early Idenitification of Progressive TB Disease Using Host Biomarkers. E Bio Medicine, 2015(2):107-108; doi:10.1016/j.ebiom.2015.01.009 (IDEA)