Despite significant progress achieved in the past years, malaria remains a major cause of morbidity and mortality, especially in children in sub-Saharan Africa. A safe and effective vaccine would represent a game changer in the fight against this disease. The malaria parasites are transmitted through the bite of an infected female Anopheles mosquito into humans, and it has different life stages (pre-erythrocytic, liver, blood and sexual stages). When developing vaccines, diff